The cell-attached soundtrack of calcium imaging

Old-school electrophysiologists like to listen to the ephys signals during experiments. For example, this allows to precisely hear when the patch pipette approaches a target neuron. The technique is discussed in the Axon Guide: “Audio Monitor: Friend or Foe?”.

The following is something very similar: Calcium imaging of neuronal activity (GCaMP6f), and an audio track that is derived from a simultaneously performed cell-attached recording of the same neuron (detected action potentials are convolved with a particular sound event, like two metals hitting each other, the sound of an anvil, and the sound of gunshots – the “firing” neuron).

Three times the same calcium recording, but with different soundtracks:

CC-BY 3.0, http://soundbible.com/1750-Hitting-Metal.html

CC-BY 3.0, http://soundbible.com/1742-Anvil-Impact-1x.html

CC-BY 3.0, http://soundbible.com/2123-40-Smith-Wesson-8x.html

This entry was posted in Calcium Imaging, electrophysiology, Imaging, Neuronal activity, zebrafish and tagged , , , . Bookmark the permalink.

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