Category Archives: Data analysis

Open access 3D electron microscopy datasets of brains

One of the coolest technical developments in neuroscience during the last decade has been driven by 3D electron microscopy (3D EM). This allowed to cut large junks of small brains (or small junks of big brains) into 8-50 nm thick … Continue reading

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How well do CNNs for spike detection generalize to unseen datasets?

Some time ago, Stephan Gerhard and I have used a convolutional neural network (CNN) to detect neuronal spikes from calcium imaging data. (I have mentioned this before, here, here, and on Github.) This method is covered by the spikefinder paper … Continue reading

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A list of cognitive biases

There are a handful of cognitive biases that are well-known to most scientists: confirmation bias, the Dunning-Kruger effect, the hindsight bias, the recency effect, the planning fallacy, loss aversion, etc.. Although they should not be taken as universal laws (for example, … Continue reading

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Layer-wise decorrelation in deep-layered artificial neuronal networks

The most commonly used deep networks are purely feed-forward nets. The input is passed to layers 1, 2, 3, then at some point to the final layer (which can be 10, 100 or even 1000 layers away from the input).  … Continue reading

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Understanding style transfer

‘Style transfer’ is a method based on deep networks which extracts the style of a painting or picture in order to transfer it to a second picture. For example, the style of a butterfly image (left) is transferred to the … Continue reading

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The most interesting machine learning AMAs on Reddit

It is very clear that Reddit is part of the rather wild zone of the internet. But especially for practical questions, Reddit can be very useful, and even more so for anything connected to the internet or computer technology, like machine … Continue reading

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How deconvolution of calcium data degrades with noise

How does the noisiness of the recorded calcium data affect the performance of spiking-inferring deconvolution algorithms? I cannot offer a rigorous treatment of this question, but some intuitive examples. The short answer: If a calcium transient is not visible at … Continue reading

Posted in Calcium Imaging, Data analysis, electrophysiology, Imaging, machine learning, Neuronal activity | Tagged , , , , | 1 Comment